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How to Treat Infertility in Hypogonadism

How to Treat Infertility in Hypogonadism

08:52 30th July 2018 | Infertility

Hypogonadism is a condition where sex glands, such as the ovaries or testes, produce little or no sex hormones. Sex hormones, such as testosterone and estrogen, are responsible for developing sexual characteristics and depending on the level of severity of the condition may result in infertility.

What are the symptoms of hypogonadism?

Symptoms are due to the lack of sex hormones produced, and the severity of symptoms will depend on when the condition started and how long the deficiency has been occurring.

As an adult male, symptoms may include:

  • Erectile dysfunction and low sperm count
  • Enlarged breasts and increased body fat
  • Loss of body hair and decreased muscle mass

For women, symptoms might include:

  • Amenorrhea (absence of menses)
  • Lack of breast development
  • Infertility

What are the types of hypogonadism?

In primary hypogonadism, the defect is in the gonad/sex glands as the sex cells do not respond sufficiently to hormonal stimulation. This can be due to genetic disorders such as Klinefelter’s or Turner syndromes, chemotherapy, or trauma.

In secondary hypogonadism, the issue lies outside of the gonad, affecting the main glands that release hormones that stimulate the sex glands. Either one’s hypothalamus or pituitary gland may not be working correctly. This may be due to inflammatory disorders, infections, obesity, or injury to the hypothalamus or pituitary gland.


Testosterone (for men) and estrogen (for women) levels can be replaced with hormone therapy, and other treatments may target specific side effects, such as having a low sex drive. For both males and females, there are hormone therapies available which can enable one to have children and overcome the fertility issues incurred by hypogonadism.

Speak to a fertility specialist at Bridge Clinic should you struggle with any issues around infertility, such as low sperm count or menstual irregularities.  


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