23:56 4th February 2017 | IVF & Mitochondria

Mitochondrial Replacement Therapy MRT Pronuclear Transfer Technique Maternal Spindle Transfer Mitochrondrial Disease Dysfunctional Mitochindria Mutations mtDNA nDNA RNA Molecules HFEA Genetic Disease Mitochondrial Replacement Theraphy Unexplained Infertility Genetic Modification

Three-parent IVF – officially known as Mitochondrial Replacement Therapy (MRT) – continues to raise concern in some circles while gaining traction in others.

MRT, through pronuclear transfer technique (more common in UK) or maternal spindle transfer, was pioneered to prevent the transmission of mitochondrial disease, a group of disorders caused by dysfunctional mitochondria, from one generation to the next

09:39 17th April 2016 | Genetic Defects

PGS Assisted Reproduction Chromosomal Defects Embryo Stage Unborn Child CVS IVF/PGS Genetic Disease Sickle Cell Disorder Genetic Abnormality Defective Genes

Pre-implantation Genetic Screening (PGS) is arguably one of the most valuable developments in the assisted reproductive world. Essentially it is a means whereby chromosomal defects, which can cause a variety of diseases, can be detected at embryo stage. This is of particular value to couples who are at risk of passing on any of their genetic defects to their unborn child.

Before PGS, the only way to diagnose a defect was to perf...